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List of Cannabinoids – Peer Reviewed Data

List of Cannabinoids


any of a group of closely related compounds which include cannabinol and the active constituents of cannabis.

The list of cannabinoids below are differentiated between major and minor occurrences within the cannabis plant. These terms are defined by National Center for Complementary and Integrative Health, or NCCIH, and can be found in a study conducted by clicking here.

Also, keep in mind that this list of cannabinoids is most likely in a constant state of change and revision. Visit periodically for the most up-to-date information. As research in the cannabis field continues to increase, so will the list of cannabinoids on both the page and the cannabinoid locator tool.

**Looking for cannabinoid information that you don’t see here? Have further questions about cannabinoids? Please email us with your request, and we will get back with you as soon as possible. Please keep in mind that this is a free service, and our queue is normally filled. 

Cannabinoids in Cannabis

Check out the tables below for a breakdown of the list of cannabinoids in cannabis. Remember, these are only the known cannabinoids found in the cannabis plant. The likelihood of there being more cannabinoids that exist is quite high.

We’ve also included the two primary endocannabinoids, Anandamide and 2-Arachidonoylglycerol for those who are interested in what the body produces.

Search All Known Cannabinoids

Alternatively, you can manually look for a cannabinoid with the cannabinoid finder search feature above.

List of Major Cannabinoids

List of Minor Cannabinoids



All Known Cannabinoids

Each cannabinoid profile contains the name, chemical structure, how it’s used, and a list of potential therapeutic benefits. We stress ‘potential’ because even though we understand that some of these cannabinoids can help people, there haven’t been actual clinical trials on most of them – so we can’t officially make the claims. The FDA is very strict on this. All known cannabinoids do not necessarily offer benefits, so we have to be careful in this regard.

All known cannabinoids are listed here. Click on the corresponding cannabinoid to read more information on them. We separate them by major cannabinoids, and minor cannabinoids categories.

At New Phase Blends, we try hard to link all cannabinoid profiles to peer reviewed studies and trials. Contact us with any developing information you may have, and we will review it. If you have any additional information you feel would fit well in this comprehensive list of cannabinoids, please feel free to contact us.

Cannabinoids In Cannabis

Different Types of Cannabinoids

There are, generally, three different types of cannabinoids that we refer to:

  1. Phytocannabinoids
  2. Endocannabinoids
  3. Synthetic Cannabinoids

Phytocannabinoids are plant chemicals, found mainly in cannabis plants. Endocannabinoids are naturally made by our bodies, and are essentially lipid-based neurotransmitters. Synthetic cannabinoids are exactly that – man made.

What are Minor Cannabinoids?

Minor cannabinoids are contained within cannabis, but in lesser amounts than major cannabinoids. It is becoming more and more difficult to classify minor vs. major cannabinoids, because of how good humans are at making specialized strains. These strains can be high in almost any cannabinoid you can think of, although some are easier to produce en masse than others.

Cannabinoids and the Human Body

Many people are trying to appreciate cannabis’ anti inflammatory benefits as it slowly acquires legal status worldwide. After all, mental disorders, chronic pain, and even numerous chronic illnesses are all on the list of conditions for cannabis use. This is one of the reasons products like CBD oil or CBD balm have become so popular.

Potentially hundreds of specialized cannabinoids in the cannabis plant have been found to provide therapeutic efficacy, lifestyle enhancement, and even performance improvement to humans. Medical cannabis has been discovered to have a wide range of health benefits for persons suffering from sickness, including eliminating malignant tumors, anxiety and depression, relieving arthritis pain through anti-inflammatory effects, and reducing the number of seizures experienced by epileptic children.

This list of cannabinoids contains the most well-known and studied of these compounds. Tetrahydrocannabinol (THC) is the most well-known cannabinoid, and it’s the chemical responsible for much of cannabis’ psychoactive (psychotropic) and euphoric effects, as well as being used to treat serious diseases like PTSD and cancer. Cannabidiol (CBD), a generally non-psychoactive compound that has been proven to give a wide range of medical advantages, including pain relief, anxiety relief, and depression relief, is another noteworthy cannabinoid.

Like THC, CBD offers therapeutic benefits – but without the high. All of these benefits are thanks to the endocannabinoid system.

Related: What Does CBD Stand For?

The Endocannabinoid System

Because the endocannabinoid system is found in all mammals, companies and product lines specialized in the health and well-being of domestic pets are starting to appear in legal cannabis marketplaces. Many cannabinoids in cannabis are important to identify, because medical studies show they might improve illnesses like arthritis, digestive difficulties, anxiety, and discomfort.

CB1 and CB2 Receptors

Internally produced cannabinoids (called endocannabinoids) and phytocannabinoids interact with the Endocannabinoid System through specialized cellular receptors (largely in the nervous system) known as CB1 and CB2 receptors, discovered in the 1990s. CB1 receptors are situated in the brain and central nervous system. In contrast, CB2 receptors are found in the immune system’s organs and tissues, such as the thymus, skin, lymph nodes, bone marrow, spleen, colon, and mucous membranes of the genitals, nose, bladder, and throat. Both can utilize cannabinoids in one way or another.

As you can see in the image above, our bodies are filled with CB1 and CB2 receptors.

Brain Receptors

Where Are These Cannabinoids Found?

Before we go any further, it’s important to distinguish something: cannabinoids in cannabis are known as ‘phytocannabinoids.’ Cannabinoids produced by the human body are known as ‘endocannabinoids.’ The endocannabinoid system can utilize both cannabinoids, and phytocannabinoids.

Cannabinoids can be found in practically every part of the cannabis plant; however, the flowers contain the most. Cannabinoids are abundant on trichomes, which are hair-like structures on cannabis plant flowers. Cannabinoids were formerly thought to be only found in the cannabis plant, but studies have discovered that they may also be found in carrots, broccoli, ginseng, echinacea, and black pepper. That said, the cannabis plant is still regarded as the richest source of cannabinoids.

How are Cannabinoids Used?

We briefly covered the endocannabinoid system, but not how the cannabinoids are actually used in the human body. The cannabis plant contains well over 124 known cannabinoids, but what does this have to do with cannabis’ medical properties? I’m glad you asked!

Phytocannabinoids, or cannabinoids derived from cannabis, are structurally identical to endogenous cannabinoids made by the body. They can mimic endocannabinoids and bind to specific endocannabinoid receptors to change how the human body sends or receives messages using the central nervous and immune systems.

Endocannabinoid System Receptors

In the body, different cannabinoids have distinct effects. Tetrahydrocannabinol, for example, is known to have a high propensity for CB1 receptors, which are the brain’s endocannabinoid receptors. Tetrahydrocannabinol binds to CB1 receptors in the brain rapidly, resulting in the intoxicating effects that we’ve come to expect from high-THC cannabinoids. This is why THC is a psychoactive cannabinoid.

CBD (cannabidiol) is thought to interact differently with endocannabinoid receptors. According to researchers, it may bind indirectly, affecting the ability of the endocannabinoid receptor to bind with other cannabinoids. In other words, CBD may prevent specific neurotransmitters from reaching the brain, such as those that transmit pain.

Simply said, cannabinoids interact with the human body’s endocannabinoid system, which means they have the potential to affect a variety of regulatory activities such as appetite, mood, pain threshold, and more. More study is needed to validate the health benefits of CBD and other phytocannabinoids.

Endocannabinoid System Receptors

Which Cannabinoids are the Most Common?

We noted that cannabis contains well over 124 cannabinoids, but only a few have been well studied. Even so, we only have a limited amount of study on most cannabinoids, and our understanding of how to administer cannabinoids for therapeutic effects is still developing.

Most people are familiar with tetrahydrocannabinol (THC) and cannabidiol (CBD). While THC and CBD are definitely important cannabinoids, there are many more worth exploring. While the endocannabinoid system can utilize THC and CBD, it can also utilize a LOT more cannabinoids.

What are the Top 10 Cannabinoids?

It is hard to claim that some cannabinoids are the ‘top’ ones, because they are all so different. That said, several cannabinoids are beginning to show up in wellness supplements and even certain pharmaceutical drugs. The following are the 10 most common cannabinoids found today:

As you browse the list of cannabinoids New Phase Blends has data on, you’ll notice an A or a after the abbreviated cannabinoid name. This represents cannabinoid acids. Cannabinoid acids are simply acidic forms of the cannabinoid.

Related: CBDa vs CBD

Every cannabinoid starts their journey in an acidic form. After exposed to heat, they turn into their non-acidic forms. You can still find benefits from acidic cannabinoids, like anti inflammatory properties and other medical benefits.

The Gift of the Cannabis Plant

Synthetically produced cannabinoids are anticipated to become more prevalent, because of how useful cannabinoids found in cannabis are for us. Nabilone and dronabinol are two licensed medications that are currently available that use them for medicinal benefits.

More therapeutic medications containing chemical ingredients for our endocannabinoid systems are likely to emerge as more studies on cannabinoids in cannabis genomes occur. There’s much more to this than simply THC and CBD – these are only the popular cannabinoids.

Cannabis Plant Family

Cannabinoids are studied in a variety of ways, from a physiological, to biochemical, and chemical means of operation. This is the best way to find out potential medicinal benefits. Cannabis is increasingly being viewed as more than just a way to get high in North America. Using cannabinoids as medicine is gaining traction among many people, from lawmakers to celebrities, to regular folks like you and me.

For far too long, research into cannabis’ therapeutic benefits has been stifled. I mean, we’ve had an endocannabinoid system for this long and only recently did we discover this. Fortunately, this is changing in the U.S., which is on track to overtake Spain, Israel, Italy, and Canada as a global leader in research on cannabinoids’ medical qualities.

The human body can benefit so much from the continued studies on cannabinoids found in cannabis.

Whether cannabis is used for medicinal purposes or to get high, one thing is certain: cannabis, and the chemicals found in cannabis, is becoming a bigger part of American society every year.

Cannabinoid Production

Cannabinoid Biosynthesis
Photo credit: Frontiers in Plant Science

Cannabinoid production occurs in both cannabis sativa, and cannabis indica, via cannabigerolic acid (CBGa). CBGa, also known as the mother cannabinoid, then undergoes different processes which causes it to transform into other cannabinoids.  Cannabinoids are synthesized through a common pathway in trichomes, like the one you see in this picture. They are biosynthesized in the buds of female flowers. Cannabinoid content is quite low in male flowers.

Did you know that the cannabis plant also uses the trichrome to act as a first line of defense?

Cannabinoid production occurs in both cannabis sativa, and cannabis indica, via cannabigerolic acid (CBGa). CBGa, also known as the mother cannabinoid, then undergoes different processes which causes it to transform into other cannabinoids.  Cannabinoids are synthesized through a common pathway in trichomes, like the one you see in this picture. They are biosynthesized in the buds of female flowers. Cannabinoid content is quite low in male flowers.

Did you know that the cannabis plant also uses the trichrome to act as a first line of defense?

Cannabinoids In A Trichrome

The plant will use them to shield itself from harm caused by different animals and insects. There are even some species of fungi that are deterred by these trichromes. The trichromes are filled with terpenes, which give off a distinct defensive smell, and TONS of cannabinoids. Our bodies can utilize these different cannabinoids similar to how endocannabinoids are used. There is a lot more to it, but this is the basic premise.  

Endocannabinoids vs Cannabinoids

Endocannabinoids are produced by the human body. Phytocannabinoids, or simply cannabinoids, are found within the cannabis plant family. Cannabinoids are largely located in the sticky resin that is produced by the cannabis plant. The proper name of this resin is a ‘glandular trichome.’

Check out this picture of the processed resin:

Cannabis Resin Containing Cannabinoids

Different Cannabinoid Comparisons

Common Questions About Cannabinoids

How Many Cannabinoids Are There?

There are well over 100 different cannabinoids, with that number nearing about 124. Scientists are sure there are more, but they need to conduct more research to find them.

What is the Strongest Cannabinoid?

This is a tough question, because strongest could mean a number of different things. If you take a look at terms of intoxication levels, Delta 9 THC is probably the ‘strongest.’

It has a strong binding affinity for the CB1 receptor, and it can cause people to get high from eating it, or smoking it.

Which Cannabinoid is the Most Psychoactive?

Delta 9 THC is, by far, the most psychoactive cannabinoid that we know about today. A close second would be Delta 8 THC, but since the intoxicating effects that Delta 8 brings last much shorter, the winner for this category does to Delta 9.

What is the Strongest Hemp Cannabinoid?

While we are still figuring out more about this plant chemical (almost on a weekly basis), it seems that Cannabidiol (CBD) is the strongest – at this point in time.

Remember, we are in our infancy when it comes to cannabinoid research. Check back frequently for updated responses as more studies are completed.

What Are the Top 10 Cannabinoids?

To be fair, there really are no recognized “top 10” cannabinoids. For that reason, this answer will vary depending on who you ask. If you classify them in popularity, the following should make most top 10 lists of cannabinoids:

These are in no particular order. As research develops, this list will likely change.

What Cannabinoids Get You High?

Forms of the cannabinoids known as tetrahydrocannabinol, or THC, can get people high. This is why THC is considered a controlled substance. There are several different forms of THC, and while some get people more high than others, they will all get you intoxicated in some way.

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