Free Shipping Within the US
Money Back Guarantee


Dale blog imageAuthor: Dale Hewett
Table of Contents (Scrollable)

There are plenty of cannabinoids in cannabis. Most people understand this by now. While there are several popular cannabinoids, there are also an overwhelming amount of what I would call a fringe cannabinoid. Cannabigerol Monoethylether, or CBGM, is one of these strange derivatives.

What is Cannabigerol Monoethylether (CBGM)?

For starters, CBGM is a derivative of CBG. Cannabigerol, also known as CBG, is a group of cannabinoids found in the cannabis plant.

Unlike THC, CBG (and many of its derivatives) are not intoxicating at all. Instead, it is reported that CBG actually blocks the psychoactive effect of THC while still providing the body with potential medicinal benefits. Part of the CBG family of phytocannabinoids is the cannabinoid known as cannabigerol monomethyl ether (CBGM)

CBGM was discovered in 1968 by scientists from Kyushu University in Japan. The compound was discovered from a Japanese cannabis strain called Minamioshihara No. 1.

Raw Hemp Flowers

When the scientists were using acid to separate compounds from the cannabis plant, they discovered a pale-yellow colored syrup-like substance which was later called CBGM.

They were also able to derive the compound through the process of methylation; this involves the process of adding methyl molecules. CBGM is one of the two cannabinoids in the CBG family that is considered in ether formation. 

At this time, many cannabinoids are still undergoing research. Though little is known about this compound (CBGM), the limited knowledge available about it is derived from CBG.

There is hope that more research on CBGM will be conducted which will help us fully understand the compound and its effects.

How Does CBGM Work In Our Bodies?

Apart from the molecular structure, researchers are yet to know what makes CBGM different from the CBG family in regards to how it works within us.

There are possibilities that the compound might affect the body the same way other cannabinoids. However, since CBGM is an ether compound, this could cause it to affect the body differently from other cannabinoids.

Generally speaking, CBG-derived cannabinoids are said to interact with the body by impacting the Endocannabinoid System (ECS) of the body.



Endocannabinoids are naturally produced cannabinoids by the body that are responsible for the regulation of physiological functions and maintenance of internal balance.

This same system can utilize phytocannabinoids, like CBGM, to influence certain effects. For instance, the reason people get high after consuming THC is because of how THC interacts with the CB1 cannabinoid receptor. This receptor is part of the endocannabinoid system.

Endocannabinoid System Receptors

Are There Benefits to Using CBGM?

To fully understand the therapeutic effects of CBGM, more research has to be done. We simply do not know, for sure, how it might help us. One can only speculate that since CBGM is a member of the CBG family of cannabinoids, it may provide the same medicinal benefits.

Related: Benefits of CBD Use

If CBGM imitates the therapeutic effects of CBG, then it has potential in helping patients with the following conditions;


There are reports that CBG can treat glaucoma by reducing the painful intraocular eye pressure.

Although the study has only been done on study rats, scientists are confidents that the compound might have the same effects if used on humans.  

Anti-inflammatory effects

It was reported that CBG showed excellent anti-inflammatory effects, similar to CBD. The study was done on lab rats with inflammatory Bowel Diseases; ulcerative colitis and Crohn’s disease, and they benefitted from the compounds’ anti-inflammatory therapeutic benefit. 

CBG is also reported to have anti-cancer and analgesic benefits. It is also capable of reducing nausea.

Another study done on rat models showed that CBG is capable of treating neurodegenerative diseases like Huntington’s diseases. 

Interesting Facts About CBGM

  • Synonyms: O-methyl Cannabigerol | Cannabigerol monomethyl ether
  • Formal name: 2-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3-methoxy-5-pentyl-phenol
  • Molecular formula: C22H34O2
  • Molecular weight: 330.5


COLASANTI, B. K. (1990). A Comparison of the Ocular and Central Effects of Δ9-Tetrahydrocannabinol and Cannabigerol. Journal of Ocular Pharmacology and Therapeutics, 6(4), 259–269.

Borrelli, F., Fasolino, I., Romano, B., Capasso, R., Maiello, F., Coppola, D., … Izzo, A. A. (2013). Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. Biochemical Pharmacology, 85(9), 1306–1316

Banerjee SP, Snyder SH, Mechoulam R. Cannabinoids: influence on neurotransmitter uptake in rat brain synaptosomes. J Pharmacol Exp Ther. 1975;194(1):74-81.] than THC. 

Back to List of Cannabinoids

blog BG
Table of Contents

Search our website for more information on CBD:

Related Cannabinoids

Commitment to Trusted Information on CBD

When it comes to understanding both the science and benefits of cannabidiol (CBD), it is extremely important that you can trust the source of your information. This is exactly why our team at New Phase Blends includes experts in the field of cannabinoid research and development, including frequent correspondence with certified medical professionals and PhDs in relevant fields via studies, research, and additional peer reviewed pieces of information. All information published is reviewed and checked for accuracy. We pride ourselves on staying up-to-date with the latest scientific research and clinical studies related to not only CBD, but also its effects on the human body.

Our website also includes an About Us page, where you can learn more about our team, mission, and commitment to providing accurate, reliable information about CBD. Users can access this from the header menu at the top of the screen. Additionally, all of our products are third-party lab tested for quality and purity, and we make the results of these tests easily accessible to our customers.

User Experience Strengthened Through The Use of AI Content

Some articles you read may contain content created by the use of AI tools. This content is always edited by a human. We fact check any AI content, and ensure the information produced is accurate, up to date, and relevant to the article it may be contained in. All content is verified against peer reviewed data on CBD written by PhD’s and respective experts in their field of medical science.

Our goal in using AI content is to increase the user experience by increasing content production, and quality. This results in more information becoming available to the reader more frequently.

About the Author - CBD Expert Dale Hewett

Dale Hewett Author
Dale Hewett

Dale Hewett is the owner and founder of New Phase Blends. He discovered his passion for CBD use after suffering from injuries sustained while on Active Duty in the US Army. His number one priority is introducing the same CBD products that he himself uses for relief to others who can benefit from them.

Dale holds a Master Degree of Science, and is the inventor of the popular, CBD-based sleep aid known as ‘Sleep.’ He’s given multiple lectures on CBD to institutions such as Cornell’s MBA student program, and Wharton’s School of Business.

la wire logo
yahoo finance greyscale
forbes logo
Markets Insider Logo
chicago journal logo greyscale