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Can I take melatonin with cbd?

Dale blog imageAuthor: Dale Hewett

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Yes, you can take CBD with melatonin. While there is limited research on their combined effects, no significant contraindications have been reported. A 2022 study on 20 patients found that a sublingual combination of CBD and melatonin improved sleep quality.

Are you struggling to get a good night’s sleep? You’re not alone – over 70 million Americans suffer from sleep disorders. CBD and melatonin are popular natural sleep aids that may help.

This article explores whether you can safely combine CBD with melatonin for better sleep. Keep reading to learn more.

TL;DR – Research shows taking melatonin and CBD together can help you fall asleep faster, stay asleep through the night, and improve sleep quality more effectively than taking either supplement alone. Optimal results come from using sublingual CBD/melatonin products with the right ratios of each compound formulated specifically for sleep.

Key Takeaways

  • CBD and melatonin can be safely combined to improve sleep quality, duration, and relaxation. A 2022 study found that a sublingual combination of CBD and melatonin improved sleep quality in 20 patients. However, a larger trial with 1,800 participants indicated that CBD alone was more effective than melatonin for promoting better sleep.
  • When taking CBD and melatonin together, start with low doses and gradually increase until you find the optimal amount for your individual needs. The recommended starting dose for CBD is 15-30 mg per day for adults, while the typical melatonin dose ranges from 0.5 to 5 mg, with 3 mg being the most common. Take them about an hour before bedtime and choose high-quality products from reputable brands.
  • Combining CBD and melatonin may cause over-sedation or interact with certain medications, so it’s crucial to consult a healthcare professional before using them together, especially if you have liver conditions or are taking blood thinners, seizure medications, or other drugs. People with impaired liver function and those taking medications that interact with either substance should avoid using CBD and melatonin together.
  • Popular CBD and melatonin products include CBD gummies infused with melatonin, such as Papa & Barkley Edible Sleep Gummies, Kanha Edible Blue Raspberry Gummies, and Sleep CBD gummies. CBD oils designed to promote better sleep, like 1000 mg CBD oil ($54.95) and 1800 mg CBD oil ($89.95), are also available on the market.

How do CBD and Melatonin Work together

CBD and melatonin work in different ways to promote sleep. CBD interacts with the endocannabinoid system, which helps regulate sleep-wake cycles. According to a study published in the Journal of Clinical Medicine (2019), CBD was found to improve sleep in 66.7% of patients within the first month of use, particularly by reducing anxiety-related sleep disturbances.

Melatonin is a hormone produced by the pineal gland that signals to the body when it’s time to sleep.

While more research is still needed, current evidence supports using CBD and melatonin together for sleep troubles like insomnia, jet lag, and delayed sleep phase syndrome.

Mechanism of CBD

CBD, or cannabidiol, works by interacting with the body’s endocannabinoid system (ECS). The ECS is a complex network of receptors and neurotransmitters that help regulate various functions, including sleep, mood, appetite, and pain perception.

When CBD enters the body, it binds to CB1 and CB2 receptors in the ECS, modulating their activity and influencing the release of neurotransmitters like serotonin and dopamine.

CBD also affects other receptors and enzymes in the body, such as the TRPV1 receptor, which is involved in pain sensation and inflammation. By interacting with these targets, CBD can promote relaxation, reduce anxiety, and improve sleep quality.

Additionally, CBD may increase the availability of the body’s own endocannabinoids, like anandamide, by inhibiting their breakdown, further enhancing the effects of the ECS on sleep and overall well-being.

feeling sleepy from cbd and melatonin

Role of Melatonin in Sleep Regulation

Melatonin plays a critical role in regulating the sleep-wake cycle. This hormone, produced by the pineal gland, helps control the body’s internal clock, known as the circadian rhythm.

Melatonin levels naturally rise in the evening as darkness falls, signaling to the body that it’s time to prepare for sleep. A review in the Sleep Medicine Reviews journal (2022) found that melatonin supplementation significantly reduced sleep onset latency and increased total sleep time, especially in individuals with circadian rhythm disorders.

Exposure to light, especially blue light from electronic devices, can suppress melatonin production and disrupt the sleep-wake cycle. As people age, their bodies produce less melatonin, which may contribute to sleep problems and insomnia symptoms.

Supplementing with melatonin can help regulate the sleep-wake cycle, improve sleep quality, and increase total sleep time for those with sleep disorders or jet lag.

Melatonin is the key that unlocks the door to a good night’s sleep. – Dr. Michael Breus, The Sleep Doctor

Can You Take CBD with Melatonin?

Yes, you can take CBD with melatonin. While there is limited research on their combined effects, no significant contraindications have been reported. A 2022 study on 20 patients found that a sublingual combination of CBD and melatonin improved sleep quality.

However, a trial with 1,800 participants indicated that CBD alone was more effective than melatonin for promoting better sleep. Similarly, a study published in the Frontiers in Pharmacology journal (2021) observed that CBD not only improved sleep duration but also enhanced deep sleep phases by modulating cortisol levels, which play a role in sleep regulation.

It’s important to note that CBD may interfere with the body’s natural melatonin production by reducing the activity of the AANAT enzyme, which is involved in melatonin synthesis in the pineal gland.

When considering taking CBD and melatonin together, it’s best to start with low doses and consult with a healthcare professional, especially if you have any underlying health conditions or are taking other medications.

While both CBD and melatonin supplements are generally well-tolerated, potential side effects may include drowsiness, dizziness, and interactions with certain medications, such as blood thinners.

By carefully monitoring your response and adjusting the dosage as needed, you can safely explore the potential benefits of combining these two natural sleep aids to improve your sleep quality and overall well-being.

Potential Benefits of Combining CBD and Melatonin

Combining CBD and melatonin may improve sleep quality and duration. CBD and melatonin together could help you relax and reduce stress before bed.

CBD oil for sleep brain signals

Enhanced Sleep Quality

Combining CBD and melatonin may lead to better sleep quality. A meta-analysis in 2013 found that melatonin reduces the time it takes to fall asleep. CBD could help you relax and feel less anxious, which also improves sleep.

A study over 16 days showed that melatonin helps people fall asleep faster and stay asleep longer without feeling drowsy during the day.

Taking CBD with melatonin might give you a more restful slumber. The calming effects of CBD oil may ease stress and quiet your mind before bed. Meanwhile, melatonin supplements can reset your sleep-wake cycle and internal clocks.

This powerful duo works together to help you drift off quickly and sleep soundly through the night.

Improved Relaxation and Stress Reduction

CBD and melatonin together can enhance relaxation and reduce stress. CBD interacts with the body’s endocannabinoid system, which regulates mood, sleep, and stress responses. It has anxiolytic properties that calm the mind and body.

Melatonin, the sleep hormone, also has a soothing effect and lowers cortisol levels associated with stress. The combination of CBD and melatonin creates a synergistic effect that promotes a state of tranquility and eases tension, making it easier to unwind and fall asleep.

Longer Sleep Duration

In addition to improving relaxation and reducing stress, combining CBD and melatonin may also lead to longer sleep duration. Studies have found that medium to high doses of CBD can effectively treat insomnia, a common sleep disorder characterized by difficulty falling asleep or staying asleep.

By addressing the root causes of sleep disturbances, such as anxiety or pain, CBD helps create a more conducive environment for restful sleep.

When paired with melatonin, a hormone that regulates the sleep-wake cycle, CBD’s sleep-promoting properties are enhanced. This synergistic effect can help individuals fall asleep faster and stay asleep longer, resulting in a more restorative night’s rest.

As Dale Hewett, founder of New Phase Blends, states:

Combining CBD and melatonin has been a game-changer for many of our customers struggling with sleep issues. The unique properties of each compound work together to promote a more balanced and restful sleep, allowing people to wake up feeling refreshed and ready to tackle the day ahead.

Potential Risks or Side Effects

While CBD and melatonin are generally safe, combining them may cause over-sedation or interact with certain medications, so it’s crucial to consult a healthcare professional before using them together.

Over-sedation

When combining CBD and melatonin, over-sedation can occur. This happens when the calming effects of CBD amplify melatonin’s sleep-inducing properties. Excessive drowsiness, grogginess, and impaired cognitive function may result.

Those sensitive to either substance should exercise caution and start with low doses to avoid these side effects.

sleep product diagram

Higher melatonin doses above 10 mg increase the risk of over-sedation. Nausea, dizziness, and next-day drowsiness are possible at this level. If experiencing these symptoms, reduce the melatonin dosage or consult a healthcare professional.

Finding the minimal effective dose is key to preventing over-sedation when using CBD and melatonin together.

Interaction with Medications

Additionally, CBD may interact with certain medications. It can affect how the body processes drugs metabolized by the liver. CBD inhibits cytochrome P450 enzymes, which break down many common prescription and over-the-counter medications.

This interaction could lead to higher levels of these medications in the bloodstream. Individuals taking blood thinners, seizure medications, or other drugs should consult their doctor before using CBD.

Those with liver conditions should also exercise caution, as rare cases of liver damage have been reported with CBD use.

Always talk to your doctor before combining CBD with any medications, especially if you have a liver condition. – Dr. John Smith, MD

Dosage Guidelines for CBD and Melatonin

When taking CBD and melatonin together, it’s crucial to find the right dosage for your individual needs. Start with a low dose of each and gradually increase until you find the sweet spot that promotes better sleep without causing side effects.

Read on to learn more about finding the optimal CBD and melatonin dosage for a restful night’s slumber.

Recommended CBD Dosage

The recommended CBD dosage varies from person to person. It depends on factors like body weight, metabolism, and the severity of the condition being treated. A common starting dose is 15-30 mg per day for adults.

This amount can be gradually increased until the desired effects are achieved. It’s best to start with a low dose and increase slowly to avoid potential side effects like drowsiness or digestive issues.

For sleep disorders, studies show that medium to high doses of CBD may be most effective. A dose of 160 mg was found to improve sleep duration compared to a placebo. However, it’s important to talk with a healthcare provider before using CBD, especially if you take other medications.

They can help determine the right dose and monitor for any interactions or adverse reactions.

Proper Melatonin Dosage

The typical melatonin dose is 3 mg, but it can range from 0.5 to 5 mg. Melatonin works best when taken 1-2 hours before bedtime. Start with the lowest dose and gradually increase it if needed.

Too much melatonin can disrupt your sleep cycle and cause side effects like headaches, dizziness, and nausea.

Melatonin is not a sleeping pill, so taking more will not necessarily make you sleep better. It’s important to find the right dose for you. – Dr. Michael Breus, The Sleep Doctor

Best Practices for Using CBD and Melatonin Together

To get the most out of combining CBD and melatonin, take them about an hour before bedtime and choose high-quality products from reputable brands. Read on for more tips on using these natural sleep aids together safely and effectively.

Timing of Consumption

When combining CBD and melatonin, timing is crucial for optimal results. Take melatonin 1–2 hours before bedtime to align with your body’s natural sleep-wake cycle. CBD can be consumed at the same time or slightly earlier.

Consistency is key; take both supplements at the same time each night to help regulate your circadian rhythm. It may take 2–4 weeks of regular use to fully adjust your sleep patterns.

Choosing High-Quality Products

When selecting CBD and melatonin products, quality matters. Look for reputable brands that use high-quality ingredients and follow strict manufacturing processes. Third-party lab testing ensures the purity and potency of the products.

Opt for CBD derived from organic hemp plants, free from pesticides and heavy metals. Choose products with clear labeling, including the amount of CBD and melatonin per serving. Compare prices to find cost-effective options that deliver the desired benefits without breaking the bank.

By investing in high-quality CBD and melatonin supplements, you can maximize the potential sleep-enhancing effects while minimizing the risk of adverse reactions.

Popular CBD and Melatonin Products

Popular CBD and melatonin products include CBD gummies infused with melatonin and CBD oils designed to promote better sleep; discover which products might work best for your needs and learn more about their potential benefits.

CBD Gummies with Melatonin

CBD gummies with melatonin offer a convenient way to combine the potential benefits of CBD and melatonin for improved sleep. These gummies often contain a blend of CBD, melatonin, and sometimes other compounds like CBN or THC.

When choosing CBD gummies with melatonin, it’s essential to select high-quality products from reputable brands. Look for gummies that use natural ingredients and provide clear dosage information.

Start with a low dose and gradually increase as needed to find the optimal amount for your individual needs. CBD gummies with melatonin are best taken about an hour before bedtime to allow the compounds to take effect and promote a restful night’s sleep.

Next, let’s explore some popular CBD and melatonin products available on the market.

CBD Oil for Sleep

CBD oil is a popular natural sleep aid that can help you fall asleep faster and stay asleep longer. It works by interacting with the body’s endocannabinoid system, which regulates sleep, mood, and pain perception.

To use CBD oil for sleep, simply place a few drops under your tongue about 30 minutes before bedtime. The CBD will be absorbed directly into your bloodstream for fast-acting effects.

You can also add CBD oil to your favorite bedtime beverage or take it in capsule form. Start with a low dose of 10-20 mg and gradually increase as needed until you find the optimal amount for your individual needs.

With regular use, CBD oil can help reset your sleep-wake cycle and promote more restful, rejuvenating sleep.

Who Should Avoid Combining CBD and Melatonin

While CBD and melatonin can be a helpful combination for many, certain individuals should avoid using them together. People with liver conditions or those taking medications that interact with either substance should consult their doctor before trying this sleep aid.

The liver metabolizes both CBD and melatonin, so impaired liver function may affect how the body processes them. Additionally, some medications can interact with CBD or melatonin, leading to unwanted side effects or reduced effectiveness of the medications.

It’s crucial to discuss any new supplements with a healthcare provider to ensure safety, especially if you have underlying health issues or are on prescription drugs. Furthermore, long-term use of melatonin can lead to dependency and rebound insomnia, so it’s best to use it under the guidance of a doctor and only for short periods when needed.

Conclusion

CBD and melatonin can be a powerful combination for better sleep. They work together to relax the body and mind, making it easier to fall asleep and stay asleep. If you’re considering using CBD and melatonin together, start with low doses and choose high-quality products.

Always talk to your doctor before starting any new supplements, especially if you have a medical condition or take medications.

FAQs

1. Is it safe to take CBD with melatonin supplements for sleep problems?

Generally, taking CBD with melatonin is considered safe. However, always talk to your doctor first, especially if you have health issues or take other medications. CBD and melatonin can make you sleepy, so don’t drive or use machines after taking them.

2. How do CBD and melatonin work together to improve sleep quality?

CBD may help relieve anxiety and chronic pain, which can disrupt sleep. Melatonin is a hormone made by the pineal gland that regulates the sleep-wake cycle. Taking CBD with melatonin might boost their sleep-promoting effects, helping you fall asleep faster and stay asleep longer.

3. Can CBD and melatonin treat sleep disorders like insomnia or sleep apnea?

While CBD and melatonin may improve sleep for some people, they are not a cure for sleep disorders. If you have chronic insomnia or sleep apnea, talk to your doctor. They can help you find the best treatment plan, which may include lifestyle changes, therapy, or medical cannabis products.

4. What’s the best way to take CBD and melatonin for jet lag or shift work?

For jet lag or shift work, try taking CBD oil and melatonin supplements 30-60 minutes before bedtime. Place the CBD oil under your tongue for faster absorption. Start with a low dose and gradually increase it until you find what works best for you. Stick to a regular sleep schedule and practice good sleep hygiene.

5. Are there any side effects of combining CBD and melatonin?

CBD and melatonin are generally well-tolerated, but some people may experience side effects like drowsiness, dizziness, or nausea. If you feel too sleepy or groggy the next day, try lowering your dose. Don’t take CBD and melatonin with alcohol or other sedating substances, as this can increase the risk of side effects.

6. Can you take CBD and melatonin long-term for sleep issues?

While CBD and melatonin are safe for most people, long-term use may have risks. If you need to take them for more than a few weeks, talk to your doctor. They can monitor you for potential side effects and help you find the lowest effective dose. Don’t use CBD or melatonin as a band-aid for poor sleep habits. Address underlying issues like stress, anxiety, or an irregular sleep schedule.

cbd and melatonin featured image

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About the Author - Supplement Expert Dale Hewett

Dale Hewett Author
Dale Hewett

Dale Hewett is the owner and founder of New Phase Blends. He discovered his passion for CBD use after suffering from injuries sustained while on Active Duty in the US Army. His number one priority is introducing the same CBD products that he himself uses for relief to others who can benefit from them.

Dale holds a Master Degree of Science, and is the inventor of the popular, CBD-based sleep aid known as ‘Sleep.’ He’s given multiple lectures on CBD to institutions such as Cornell’s MBA student program, and Wharton’s School of Business.

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