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How Long Does CBD Take to Work

In order to answer the question of how long does CBD take to work, we must know two things:

  1. What is CBD?
  2. What factors affect the timing of CBD release in the body?

Studies show that CBD can enter the bloodstream between 2 minutes and two hours. This timing is determined by the way it is delivered. The method of delivery also determines the bioavailability of CBD.  After this, factors such as serving strength, quality, and spectrum type can affect how long it takes people to feel the effects of CBD.

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If you’re wondering “How long does CBD take to work,” keep reading and find out!

What Is CBD?

CBD is one of more than 120 naturally occurring cannabinoids found in cannabis sativa L. CBD formulations tested in pre-clinical studies show diverse medicinal properties, such as:

  • anti-nausea
  • anti-emetic
  • anti-tumor
  • anti-inflammatory
  • anti-depressant
  • anti-psychotic
  • anti-anxiolytic

how long does CBD take to work

Knowledge of the properties of cannabis dates back to at least 4000 B.C. All of the different varieties of cannabis, including cannabis indica, belong to the same species. All cannabis sativa plants produce active compounds. However, each variety produces these compounds in different concentrations and proportions.

These not only depend on gene background, but also on growing conditions and climate. The hemp extract used to make CBD products is a fat-based substance.

What Is Bioavailability?

Bioavailability is the proportion of a drug which enters blood circulation in our bodies. The method in which you consume CBD will affect the amount that enters the blood stream. Eating CBD will only allow a small fraction of it to enter your bloodstream.

  • Edible – 10-20% Bioavailability. Edibles can be advantageous for several reasons. A wide availability of pharmaceutical-grade compounds, standardized doses and simplicity draw people towards them. The downsides are that absorption is slow and erratic. Maximum concentrations typically occur within 60-120 minutes.
  • Topical – 10-20% Bioavailability. Topical administration delivers drugs through placing substances directly onto the skin. Doing so allows a steady amount of a drug to be delivered over a period of time. This makes it ideal for localized pain relief. It avoids first pass metabolism. CBD has a hard time penetrating the skin’s water barrier. This requires a relatively strong formulation.
  • Transmucosal/Sublingual – 34-36% Bioavailability. This method has several advantages. The sublingual vein is covered by a thin mucosa that is very vascular. This means that a drug can be transferred quickly through the cell layer under your tongue. After this, it gets directly into your blood circulation. This also avoids first pass metabolism.

an image of the sublingual vein

  • Pulmonary – 2-56% Bioavailability. Inhaled cannabinoids produces a fast effect. Cannabis related effects generally begin within a few minutes of the first inhalation (smoked or vaporized) and these effects can increase []. A peak value occurs after 10 min, and can maintain at a steady state for 3–5 h.

First Passage Metabolism

The first pass effect occurs when a drug gets metabolized in the body. A reduced amount of the active drug enters your bloodstream after this happens.

The first pass effect occurs by the liver filtering substances. In this case, the substance is CBD. Due to differences among individual patients, this can make accurate dosing hard.

Anytime you eat or drink anything, the first pass metabolism will occur. Our digestive system’s end up filtering out or destroying a lot of the nutrients when we consume things. This is not specific to CBD. It happens to almost everything we consume.

Considering CBD edibles? It may take some time to determine how much or little works for you, because of this effect. This doesn’t mean that CBD edibles are bad, or should be avoided. Everyone has different preferences for how they supplement with certain things. Just keep this in mind when taking items like CBD pills, beverages, or gummies.

CBD Dosage and Potency

The dosage and potency of your CBD product is as important as the consumption method when answering the question of how long does it take CBD to work. In essence, after your CBD gets to where it’s going (bloodstream), will there be enough to feel any different? This is what you need to keep in mind when using any supplements – not just CBD.

The research on what makes up an effective dosage is all over the place. For this reason, it’s important to really pay attention to how your body responds when taking CBD. Most avid CBD users have gone through the trial and error of using CBD. They know the right amounts to take, and the type of CBD that suits them best.

Thirty-three states have approved cannabis use for medical conditions. Remember, CBD legally  is classified as hemp. The Drug Enforcement Administration recognizes cannabis as a Schedule I drug, meaning it has no currently accepted medical use. This has stymied clinical trials.

What is shown in these trials though is a consistent reduction in symptoms of the underlining condition that CBD was used to treat.

Bottom line, finding the ideal dosage will depend on the users unique physiology. Personally, I think 25 mg a is a great daily serving to start with. However, some people take more, and some take less to feel the effects.

First time users should start with the recommended dosage by looking at the supplement facts panel on their CBD product. Use this amount, and adjust as needed. Always start with the least amount needed to get relief. Work your way up from there, if need be.

Inflammation and Pain

Pain and inflammation are the body’s way of responding to tissue injury, infection and genetic changes. There are two types of pain: acute pain and chronic pain.

Acute pain is normally local, and present in the form of a very specific, pin-point type of pain. For example, when you stub your toe on something, you are experiencing acute pain.

Chronic pain is a pain that lingers over time (often long periods of time). Have your ever had surgery? The lingering aches and pains throughout the years following the surgery is chronic pain.

CBD may effectively treat both forms of pain. How long does CBD take to work for treating these types of pain? Sublingual drops used to treat inflammatory issues can act within a matter of 10 minutes (sometimes even quicker). Edible CBD can take longer – roughly 30 minutes or more.

Conclusion | How Long Does CBD Take to Work?

Hopefully you got some benefit out of the information in this article. We pride ourselves in trying to educate others as much as possible. This way, people can make informed decisions when using and buying CBD products.

“How long does CBD take to work?” Again, there really is no specific answer to this question. Typically, it depends on the user and method of consumption.

Typically, sublingual CBD drops take effect faster than edible CBD products like drinks or gummies. That said, everyone has their own preference for how they like to supplement with CBD products.

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Experiment for yourself, and see how it works for you. Remember to make sure that you choose a quality CBD company, and premium CBD items. This can save you a lot of headache in the future. Look for things such as:

  • product certifications (GMP, organic, non-GMO)
  • money-back guarantees
  • real, positive reviews and references

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