Comparing CBC Oil and CBD Oil: What's Better and Why?

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CBC Vs CBD | What’s the Difference?

This article will address the differences of CBC vs CBD, offer some advice in purchasing CBC rich hemp oils, and help you leave with a better understanding of the CBC cannabinoid. Most of us are already familiar with two the two more-famous cannabinoids within cannabis: CBD and THC.

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While these two cannabinoids are useful, other cannabinoids have much to offer. CBC, or cannabichromene, is a lesser known cannabinoid in full spectrum CBD oil products that still hasn’t hit the limelight.


CBC hasn’t been the center of any massive research yet. However, a few smaller studies have shown this cannabinoid’s medical potential and brought more attention to further research.

Let’s compare these two cannabis compounds, the similarities they share, and the differences they have. While cannabinoids may look similar from the outside looking in, there are, in fact, a lot of differences.

Since the Farm Bill of 2018 passed, CBD has received a vast majority of the media attention. CBN and CBG, with their non-psychoactive properties, quickly followed CBD and are also available in the marketplace now. If interested, check out this article on comparing the differences between CBN vs CBD.

This goes to show the speed at which research has been conducted since industrial hemp was decriminalized. CBC will follow in these footsteps.

A Short History of CBC

It’s completely understandable if you haven’t heard about cannabichromene, or more commonly known as CBC. It was discovered in 1966 by Dr. Raphael Mechoulam and Y. Gaoni.

CBC hasn’t received too much attention to date. However, CBC is a prominent cannabinoid that has been considered for use because of its potential therapeutic benefits.

Like many other cannabinoids, CBC is commonly mistaken with CBD. CBC is a different compound and has a unique chemical structure (C21H30O2), as you can see in the info graphic above.

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When discussing CBC vs CBD, keep in mind that cannabichromene (CBC) is quickly emerging as one of the popular cannabinoids of recent times. CBD, on the other hand, remains just as prevalent if not more so than THC.  A study in 1981 assumed that CBC was the second-most abundant compound in the plant, even exceeding the quantities of CBD.

If this is true, then we desperately need to understand how to develop a CBC rich strain and determine the medicinal properties, if they exist.

Difference Between Cbc Vs Cbd

CBC gained traction right after the distinction was made between CBD and CBG. That being said, there still aren’t any cannabis Sativa strains that highlight high concentrations of CBC.

As we’ve seen with CBD, though, that could very well change and change fast. High CBD strains are now famous, and twenty years ago, they weren’t.

Extracting Cannabichromene to Make CBC Oils

When you pull out the oils from the cannabis plant, you are conducting what’s called extraction. There are many different ways to do this, and if you’re interested to learn more about it, you can click here. In this article, we’re not going to get too in depth in different extraction methods to make CBC oil.

Cbd Extraction Machines

The primary source of extracting CBC is via CBGa (cannabigerolic acid) instead of processing hemp flower or other portions of the hemp plant. Cultivators need to do this since they cannot count on harvesting high-CBC yield strains.

CBGa is a “stem cell” compound that is a precursor to many different cannabinoids.  THC, CBD, and CBC all share the same origin of formation: cannabigerol acid (CBGA). CBG converts and produces CBC in two different forms by means of an activated enzyme process.

How Enzymes Work

According to Pharmacology in Drug Discovery (2012), “Enzyme activation can be accelerated through biochemical modification of the enzyme (i.e., phosphorylation) or through low molecular weight positive modulators.”

Cbc Vs Cbd Chart
Image credit: Pharmacology in Drug Discovery, 2012

It’s difficult to make pure CBC oils because of the way it is made. For this reason, if you want to buy CBC oil, your best bet is to find a CBC rich oil. This normally comes in the form of a full spectrum CBD oil.

Potential Benefits Of CBC Oil vs CBD Oil

CBC oil has become a source of attraction in the medical field because of its’ potential therapeutic effects, just like CBD, CBN, and CBG.

The cannabis plant generates CBGA, which then turns into three significant cannabinoids: CBD, CBC, and THC. There is a little more to it, but that’s all we’ll cover for now regarding CBGA.

As a bonus, since CBC is a non-psychoactive compound, that means CBC oil would also be non-intoxicating.

Non-psychoactive compounds are always better in the medical community, because it eliminates the potential of physical addiction. The health benefits of CBC are quite promising, but they need a bit more research.

That said, the popularity of CBC oil seems to be rising. This is ANOTHER example of just how popular cannabis oils are becoming.

Related Article: CBD vs CBG What’s the Difference?

The cannabis Sativa plant is full of useful cannabinoids, and existing chemical research proves this claim. When talking about CBC vs CBD, scientists have discovered CBC’s potential value and have identified a few potential benefits of this cannabinoid.

Most premium, high-grade CBD products will come in a broad spectrum or full spectrum form. Either of these will contain both CBC and CBD. The content of both cannabinoids can be double checked by scanning the QR code on any label.

Again, any reputable CBD companies will put these QR codes on their products.

Cbd Gummies Qr Code Examples

They link to a genuine, third-party lab test that shows many different things a cannabinoid profile being one.

A Study on CBC in the Treatment of Cancers

In 2006, CBC was first researched to proclaim its potential benefits for cancer during a study to understand the effects of cannabinoids on tumor size and cancer progression.

In 2012, a breast cancer study, again, included anandamide and CBC in it’s trials. CBC has convinced scientists that it is worth-investigating because of its potential cancer-fighting and pain-relieving qualities.

There is no further research present in this regard to understanding the relation between how CBC works and cancer. That is what makes it challenging to evaluate this cannabinoid’s potential effect on cancerous cells.

As a side note, in no way, shape, or form are we telling you that CBC works in the treatment of cancer. We are simply saying it has been experimented with, in this regard, and needs more studies done.

Studies on CBC For Neurological Health

A study made on CBC in 2013 showed CBC’s potential effects for promoting adult neural stem progenitor cells (NSPCs).  These cells are an essential part of the brain.

They convert into astroglial cells. Astroglial cells handle the passage of neurotransmitters everywhere in your brain and nervous system.

The strength of these cells prevents the risks of Alzheimer’s disease and other neurodegenerative conditions. In this area, CBC has given the green light for further research in improving neurological health.

CBC May Possess Analgesic Benefits

As cannabinoids interact with different receptors located in our bodies. For example, the TRPV1 receptor is responsible for controlling the feeling of inflammatory pain in the human body. 

Cbc Vs Cbd Receptor Example

Example of an andrenergic receptor

  • CBC, in initial research, has shown that it has a higher chance of interacting with the nervous system’s TRPV1 receptors than CBD oil. It also interacts with the CB2 receptor.
  • In another study, Turner and Elsohly concluded, “Anti-inflammatory activity was evaluated by the carrageenan-induced rat paw edema and the erythrocyte membrane stabilization method. In both tests, CBC was superior to phenylbutazone.” Based on this research, CBC came about as an effective pain reliever.
  • It appears that CBC may help in relieving the pain related to arthritis and many other conditions. Again, we need more research.

CBC or CBD For Back Pain? Which Is Best?

There are no studies, to date, that address using CBC for back pain issues. Because of this, we highly recommend using CBD products for your back pain.

Many customers report their symptoms of aches and pains in their spinal region become much more manageable after using CBD-rich items.

Endocannabinoid System and CBC Interactions

We’ve done a lot of talking about CBC, CBC oil, and comparing it to CBD so far. What I’d like to take time to talk about now, is exactly how and why CBC oil seems to work well for people in certain areas of health benefits.

Ever human (and every animal for that matter) has what is known as an endocannabinoid system. This bodily system is made up of a bunch of different cells that act as receptors.

You have both the CB1 receptor, and the CB2 receptor.

Endocannabinoid System Receptors

As you can see in the chart above, these receptors are everywhere. Similar to CBD, the CBC cannabinoid works by binding to these receptors which results in different benefits.

This is why people look for a CBC oil, or at least a CBD oil that has CBC in it, like ‘pure’ by New Phase Blends.

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CBC oils can interact with the endocannabinoid system, just like CBD oils. Buy CBC oil from New Phase Blends, and try it for yourself.

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One of the most cost effective ways to buy CBC oil is to simply purchase full spectrum or broad spectrum CBD oil that contains CBC in it. Since CBC oil is so hard to mass produce, this is likely your best bet.

New Phase Blends deliberately includes CBC in our pure CBD oil line.

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The ‘pure’ product line by New Phase Blends contains good amounts of CBC in it, in addition to many other cannabinoids which offer some health benefits of their own. You’ll also receive access to the entourage effect when you use full spectrum or broad spectrum products, as opposed to something like a CBC or CBD isolate.

As you can see, the pure product line is one of the most premium hemp-derived oils you can find on the market.

It’s possible you can find something of equal value, but you will not find anything better. We actually guarantee this with a 30 day money back guarantee. Don’t like what you bought from us? Return it within 30 days of your purchase for all of your money back.

CBC vs CBD | What is the Difference?

CBC, along with THC and CBD, is one of the most prevalent compounds in cannabis.

All of the potential benefits mentioned above about CBC are based on limited research, which is still not enough to make any medical claims. It is still too early to stamp out CBD’s effectiveness for use as a cancer treatment or any other ailment.

CBC has the potential to stand out for cancer treatment, and in this area, CBC could distinguish itself from CBD. These two cannabinoids might share a few similarities when it comes to potential neurological health benefits.

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CBD has been widely studied for its potential neurological benefits, while CBC is still lacks the research.

Another difference between CBC vs CBD that received attention is cannabichromene’s visible affinity for the nervous system’s TRPV1 receptors.

CBD also interacts with the TRPV1 receptor, however, CBC shows an approximately equal affinity for both your TRPV1 and 5-HT1A receptors, which plays a role in neuropathic pain. Researchers expect CBC to be a more powerful and effective choice over CBD for inflammatory pain.

Let’s see what future studies show.

Wrapping Up | CBC vs CBD

In discussing CBC vs CBD, both cannabinoids have similarities in potential medicinal benefits. For instance, people in need of better sleep concentrate on hemp products with high concentrations of CBD, or even CBN.

In contrast, the people suffering from inflammatory pain might opt for compounds like CBC, instead of CBD.

Focusing on a particular cannabinoid doesn’t mean you have to exclude other plant compounds, as there is not a single cannabinoid that isn’t potentially beneficial in some way.

CBC hasn’t been the center of any massive research yet.

However, a few smaller studies have shown this cannabinoid’s medical potential and brought more attention to further research. Scientists are already claiming that focusing on this compound as a significant research area will open otherwise closed doors in the medical and pharmaceutical industry.

The sheer depth of the compounds within the cannabis plant is astounding, and it might be confusing for you but that’s ok! Continue to read more articles by New Phase Blends to keep up-to-date with information similar to this one on CBC vs CBD.

Current Molecular Pharmacology:
National Institutes of Health:
Pharmacology of Drug Discovery:

About the Author

Dale Hewett Author

Dale Hewett

Dale is the owner and founder of New Phase Blends. He discovered his passion for CBD use after suffering from injuries sustained while on Active Duty in the US Army. His number one priority is introducing the same CBD products that he himself uses for relief to others who can benefit from them.

Dale holds a Master Degree of Science, and is the inventor of the popular, patent-pending CBD-based sleep aid known as ‘Sleep.’

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