Is it safe to use both Accutane and CBD, together, as part of your skincare regimen? This is a question that many patients have been asking doctors if they use CBD and also have acne issues. Some people have never heard of Accutane, or CBD, and do not fully understand how they both work. Since CBD does interact with some medications, it’s best to find out before trying. In this article, we dig into the details surrounding the safety of using both Accutane and CBD as part of your skincare regimen.
What Is CBD?
What is CBD? CBD, or cannabidiol, is a plant chemical compound found in cannabis plants. It should not be confused with THC, the psychoactive ingredient that leaves you feeling high. CBD cannot, and will not, get you high. It isn’t possible. CBD comes in different forms, like gummies, tinctures, or CBD vapes.
People use CBD for the many different benefits it can give them after consuming it. Some of these benefits are: inflammation relief, pain reduction, and anti-anxiety effects.
Can Accutane and CBD Be Taken Together?
To be crystal clear, Accutane on its’ own is very harsh on the liver, and considered a very strong drug. While it can do wonders for your skin, it can really do some damage to the liver if you do not closely monitor blood work while on it.
That said, using CBD for acne in your skincare regimen will not adversely interact with Accutane. Taking CBD can cause some strange interactions with SSRI and opiates, but not Accutane.
Does CBD Oil Interfere With Accutane?
The combination of the cannabinoid known as CBD, and Accutane, does not cause any known interferences. Since Accutane is harsh on the liver, other compounds that are harsh on the liver should be avoided – like excess acetophenone or ibuprofen intake. However, CBD may interact with other medications.
Please consult with your doctor to learn more about these possible interactions.
Try Using CBD Acne Creams
Every consider using a CBD acne cream? It is worth a shot. Some people report life changing results, too, without the harsh side effects of some acne medications.

Glow, by New Phase Blends, is a CBD-based acne cream with a 1% salicylic acid mixture. The salicylic acid cleans out your pores, while the cannabidiol reduces inflammation and swelling associated with bad breakouts.
Acne creams usually help clean out your pores, but only a select few actually help address the embarrassing redness. Numerous reviews claim that their treatment of acne with CBD products, like this, were quite successful.
What Is Accutane?
Isotretinoin, or Accutane, is a powerful drug used in the treatment of acne. Accutane is commonly used 4 to 5 months for the cleaning of acne on the skin and is usually effective for all types and breakouts of acne.
What Are The Side Effects of Using Accutane?
- Dry skin, rash.
- Itching.
- Chapped, dry lips.
- Dry nose, nosebleeds.
- Dry eyes.
- Vision problems.
- Back pain, joint pain.
Does Accutane Permanently Cure Acne?
Most dermatologists agree that Accutane is one of the few medicines that can give relief from acne even after years of treatment and in some cases, it has been shown to permanently cure acne.
Is Accutane Found in Pill or Cream Form?
Accutane is prescribed by a dermatologist and is an oral medication. It is often used as a last resort when other treatments are not working to remove acne from the skin.
Does Accutane Work Well for Hormonal Acne?
In many cases, Accutane will not work well with hormonal acne even after it has been cleared from the skin. Hormonal acne needs to either subside when hormones stabilize, or be treated via something like birth control, which we will get into later on.
Does Accutane Cause Weight Gain or Weight Loss?
People who take Accutane have mentioned signs of weight gain or weight loss, however, the FDA does not mention this as one of the side effects on the label. Since a large portion of people who use it are teenagers, it is very hard to tell if weight gain is from hormones, developing bodies, or the drug itself.
Can You Wear Makeup While on Accutane?
Yes, many patients do wear makeup while taking Accutane. Many say that it helps to cover the redness of the skin that comes from treatment.

Remember to wear your sunscreen and put a good moisturizer on the skin as well.
How Does Accutane Work For Treating Acne?
Accutane shrinks the oil glands (sebaceous glands), preventing clogged pores and decreasing the growth of bacteria on the skin, and any anti-inflammatory effects on the skin. Accutane also reduces the production of oils on the skin.
At What Age Can You Start Taking Accutane?
Accutane is taken as a capsule and must be started with a prescription and recommendation from your dermatologist. However, experts say that Accutane is safest to take at the age of 12 years of age and older.
Dosage level for taking Accutane is 05 to 1 ,milligram per kilogram of weight. The doses are divided into 2 and are taken for up to 15 to 20 weeks.
How Quickly Does Accutane Work?
Accutane can begin to work on the skin in as early as 2 weeks. Patients notice the most effectiveness within 8 to 12 weeks. You’ll notice your skin begin to get extremely dry. This is a sign that the medication is beginning to work.
Special forms of lotions can be used, but they should be suggested by your dermatologist so they don’t conflict with anything.
How Do You Get on Accutane?
First and foremost, talk to your dermatologist. Some people don’t actually need Accutane, and can benefit from a less harsh form of skin treatments. If your acne is severe, and you’ve tried other forms of treatment, your dermatologist will likely start you on a regimen.
Medication Interactions With CBD: Exercise Caution
We touched on this earlier, but there are some medications that interact with CBD. Some of these are:
- a common blood thinner, warfarin.
- a heart rhythm medication, amiodarone.
- a thyroid medication, levothyroxine.
- several medications for seizure, including clobazam, lamotrigine, and valproate.
If you feel that you need to, double check with your doctor about using CBD, and double check with them to make sure it goes well with whatever medications you may be on.
CBD Oil Dosage For Acne Treatment
Speak with your doctor about recommended dosage of CBD. Figuring out how much CBD can be a bit tricky, since there are no official recommendations given by the FDA on using CBD for acne. However, experts recommend that you take about .25mg of CBD per pound of body weight. This is a good dose of CBD. This is for oral consumption.
Since CBD acne creams are topical, this dosage doesn’t apply. When using a product like glow, you should thoroughly clean your face with mild soap and water. When dry, apply a dime sized amount of cream around your face, and massage it into the skin. Do this every morning, and night.

There are many different forms of CBD, and you can find them all at New Phase Blends’ CBD store.
Summary – Mixing CBD and Accutane For Clearing Your Skin
These are some of the need to know details about using Accutane and CBD treatments, together. Always speak with your personal physician before using any products on your body or skin.
If you want to use Accutane for your acne and in need of CBD for another health illness, speak with your doctor to see if there is a way that both medicines can be taken with mixing or doing harm to your body.
While there are side effects for using both Accutane and CBD products, these are mild in comparison to the health benefits that they offer your body.
Safety should always be the most important factor when taking any medicine or starting a health regimen. Once you begin your Accutane or CBD treatments, you should notice a difference in the appearance of your skin and the way your body functions. Your skin may show redness during treatment, but this should quickly diminish over time. Your body should begin to show signs of healing with your CBD treatments. You will soon see that the investment you made was well worth it.
References
International Journal of Dermatology: https://pubmed.ncbi.nlm.nih.gov/8655244/